Fructose bisphosphate aldolase is involved in the control of RNA polymerase III-directed transcription

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ALDOB (aldolase B, fructose-bisphosphate)

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Structure of fructose bisphosphate aldolase from Bartonella henselae bound to fructose 1,6-bisphosphate

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Maf1 is involved in coupling carbon metabolism to RNA polymerase III transcription.

RNA polymerase III (Pol III) produces essential components of the biosynthetic machinery, and therefore its activity is tightly coupled with cell growth and metabolism. In the yeast Saccharomyces cerevisiae, Maf1 is the only known global and direct Pol III transcription repressor which mediates numerous stress signals. Here we demonstrate that transcription regulation by Maf1 is not limited to ...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

سال: 2014

ISSN: 0167-4889

DOI: 10.1016/j.bbamcr.2014.02.007